What are "Handshake Drugs?"

I’ve heard two songs now that use the phrase - “Soon We’ll Be Living in the Future” by Straylight Run and, of course, the song called “Handshake Drugs” by Wilco.  Googling the phrase led me to dozens of copies of the lyrics to the Wilco song, all of them confirming my impression that the lyrics don’t help you out at all.  Except that you can apparently buy them downtown.

I hate it when I’m too straight to understand the lyrics to the music I like.

Posted in Writing